HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Kinder, J. E. Articles by Reeves, J. J. Search for Related Content PubMed PubMed Citation Articles by Kinder, J. E. Articles by Reeves, J. J.

Serum LH Concentrations and Ovarian Activity in Cows with Repetitive Administration of LH-RH/FSH-RH^{1, 2, 3,}

Washington State University⁴, Pullman 99163

Abstract

Eight 2-year-old Angus heifers were assigned randomly to two groups. Treatments consisted of each animal receiving either 150 µg of LH-RH/FSH-RH in 1 ml of acidified saline or 1 ml of acidified saline alone via an indwelling jugular catheter at 4-hr intervals for 96 hr on days 16 through 19 of the estrous cycle. Blood samples were collected at various intervals before and after each administration. The second part of this study consisted of treating 20 mature Angus cows in the same manner as described above and ovariectomizing them at the end of the 96-hr injection period. No blood samples were collected in this study. The mean LH value in the LH-RH/FSH-RH-treated heifers was significantly higher than the mean of the control heifers. Peak serum LH values were significantly higher during the first half of the treatment period than the second half in the LH-RH/FSH-RH-treated animals. Serum LH values in the LH-RH/FSH-RH treated animals did return to basal levels within the 4-hr period following each injection. No detectable differences were noted in the follicular fluid volume or corpora lutea weight in the LH-RH/FSH-RH- and saline-injected cows.

¹ Scientific Paper 4266, College of Agriculture Research Center, Washington State University. Project 0137.

² The authors would like to thank Dr. R. Rippel, Abbott Laboratories, North Chicago, Ill. for providing us with pure synthetic LH-RH/FSH-RH; Dr. L. Reichert for LH used for iodination and the Endocrine Study Section of NIH for LH standards.

³ This study was supported in part by USPHS Grant from National Institute of Child Health and Human Development AM06192.

⁴ Department of Animal Sciences.