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Effect of High Dietary Molybdenum and Sulfate on Plasma Copper Clearance and Tissue Minerals in Growing Swine¹

University of Florida^,4, Gainesville 32611

Abstract

Sixteen weanling barrows were used in a 2 x 2 factorial arrangement of treatments (0 and .4% sulfate; 0 and 1,500 ppm molybdenum) to determine the effect of molybdenum and sulfate supplementation on animal performance, plasma copper clearance, and tissue copper and iron levels. A constant level of copper (17.8 ppm) was fed to all pigs. Supplemental molybdenum resulted in de- pressed growth (P < .01), and the effect was more pronounced when fed for a longer period of time (49 vs 29 days). High dietary molybdenum reduced plasma clearance of injected ⁶⁴Cu (P < .01) and reduced liver uptake of the radioisotope. High dietary sulfate enhanced plasma ⁶⁴Cu clearance (P < .01) and increased the ⁶⁴Cu content of kidney tissue. Stable copper and iron levels for kidney, heart and spleen did not differ significantly with treatment and the values appeared to be within normal range.

¹ Florida Agricultural Experiment Stations, Journal Series No. 5481.

² Present address, Maple Leaf Mills Ltd., Toronto, Canada.

³ The authors wish to acknowledge the Moorman Manufacturing Company, Quincy, Illinois and the National Feed Ingredients Association, Des Moines, Iowa for funds in support of this study.

⁴ Department of Animal Science.