HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Pento, J. T. Search for Related Content PubMed PubMed Citation Articles by Pento, J. T.

Measurement of Plasma Calcitonin In Vivo in the Pig Using A Chronically-Implanted Catheter for Infusion and Blood Sampling

College of Pharmacy and School of Medicine, University of Oklahoma^,2, Norman 73069

Abstract

A method used to monitor circulating levels of calcitonin (CT) in the pig by means of a chronically-implanted, indwelling jugular catheter was described. This catheterization method facilitated repeated infusion and blood sampling in conscious and unrestrained animals for periods of several months. Since animals with jugular catheters in place may be used repeatedly and since the CT level in the jugular blood was observed to be several-fold greater than in the peripheral circulation, this catheterization method provides: definite advantages over other sampling techniques which have previously been used to evaluate CT secretion in the pig.

¹ The author gratefully acknowledges the advice of Drs. S. M. Glick, A. Kagan and J. A. Schmidl, and the assistance of his wife, Maureen, in the preparation of this manuscript. Part of this research was conducted at Maimonides Medical Center, Brooklyn, New York. This study was supported in part by USPHS, NIH training grant AM 05551, OURI grant 111-655 and NSF grant GB-43214.

² Department of Pharmacology.