J. Anim Sci.
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J. Anim Sci. 1974. 39:331-334.
© 1974 American Society of Animal Science
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Distribution of Injected 85 SR in Tissues and Bones of Growing Pigs

L. L. Krusemark, J. Boomgaardt1, B. G. Harmon and J. J. B. Anderson2

University of Illinois at Urbana-Champaign,3, Urbana 61801

Abstract

The effect of time on the distribution and retention of intravenously injected 85Sr was studied in 16 crossbred pigs. Specific activity decreased rapidly in serum, kidney, liver and longissimus muscle. Metatarsal, turbinate, 10th rib and fibula had similar specific activities at each time determined, reaching peaks at 16 or 32 hr. post injection. The specific activity of the proximal and distal portions of the femur was maximal at 4 and 16 hr., respectively, whereas specific activity of the shaft showed linear increase through the 128-hr. period and was less than the other bone samples. These activity changes for femur ends and shaft reflect the greater metabolic activity in the areas of the epiphyseal cartilage than in the diaphysis. Turbinate 85Sr uptake relative to other bones was less than reported in 45Ca uptake studies. Considering the bones sampled in the present experiment, the proximal portion of the femur appears to be the site of maximum metabolic activity in the skeleton of the young pig. In this experiment both the distribution and retention of 85Sr were time dependent and appeared to reflect the normal physiological growth process.

Footnotes

1 Present address: Maple Leaf Mills Ltd., 417 Queen's Quay West, Toronto, Ontario, Canada.

2 Present address: Division of Orthopaedic Surgery, University of North Carolina, School of Medicine, Chapel Hill 27514.

3 Department of Animal Science.






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Copyright © 1974 by the American Society of Animal Science.