J. Anim Sci.
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J. Anim Sci. 1974. 38:1224-1228.
© 1974 American Society of Animal Science

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Porcine Corticosteroid-Binding Globulin: Binding Properties and Levels in Stress-Susceptible Swine1, 2,

D. N. Marple3, R. G. Cassens3, D. G. Topel4 and L. L. Christian4

University of Wisconsin,3, Madison 53706 and Iowa State University,4, Ames 50010

Abstract

Corticosteroid binding activity was estimated by a modified protein binding technique in plasma samples from three swine herds. Swine from a herd bred to be stress-susceptible had significantly higher mean plasma cortisol and corticosteroid-binding globulin (CBG) levels with a significantly lower mean cortisol-CBG association constant than normal swine. The data suggest that boars have higher CBG levels than barrows and gilts. No significant relationships could be established between CBG activity and carcass traits of gilts or boars. Information suggesting thyroid hyperactivity in stress-susceptible swine is presented.


Footnotes

1 Research supported by the College of Agricultural and Life Sciences, University of Wisconsin, Madison, by ARS, USDA Cooperative Agreement No. 12-14-100-11, 214(44) and by Public Health Service Grants FD-00107-14 and 1 F02 AM 53796-01. Muscle Biology Manuscript No. 63.

2 The technical assistance of Mrs. Nancy Swatland is gratefully acknowledged.

3 Department of Meat and Animal Science.

4 Department of Animal Science.




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