J. Anim Sci.
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J. Anim Sci. 1974. 38:271-278.
© 1974 American Society of Animal Science

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Estrus, Ovulation Rate and Body Composition of Selected Strains of Mice on Ad Libitum and Restricted Feed Intake1

H. H. Meyer2 and G. E. Bradford

University of California,3 Davis 95616

Abstract

Three lines of mice differing in body weight and ovulation rate were compared under three levels of feed intake to study the importance of genotype-environment interactions for reproduction raits and body composition. The lines were: C, an unselected control; O, previously selected for increased ovulation rate; and G, previously selected for rapid growth from 3 to 6 weeks. The High treatment was ad libitum feeding, while Medium and Low treatments were designed to produce mating weights of 90% and 80%, respectively, of their respective High treatment groups. Treatments commenced when mice were 6 weeks of age and continued until mating at 10 weeks.

Line effects were significant for ovulation rate, proportion mated, pregnancy rate and percent body fat, and line x treatment interactions were significant for days to mating and percent body fat. Both line and line x treatment interaction effects were due primarily to differential performance of line G mice. Feed restriction reduced ovulation rate, increased time to mating and increased the incidence of cumulus breakdown at autopsy in mice of lines C and O. The effects of feed restriction on these traits were considerably less or absent for line G.


Footnotes

1 The assistance of Dr. D.W. Robinson with the fat analyses is gratefully acknowledged. The mouse stocks used came from a project supported by NIH Grant HD00134 and Health Science Advancement Award RR06138.

2 Present address: Department of Genetics, University of Minnesota, St. Paul 55101.

3 Department of Animal Science.







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Copyright © 1974 by the American Society of Animal Science.