J. Anim Sci.
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J. Anim Sci. 1973. 37:1376-1379.
© 1973 American Society of Animal Science
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Induction of Ovulation in Pigs with Gonadotrophin Releasing Hormone1

R. D. Baker2, B. R. Downey3 and H. J. Brinkley4

Macdonald Campus of McGill University, Ste. Anne de Bellevue, Quebec , Ayerst Research Laboratories, Chazy, New York and University of Maryland, College Park 20740.

Abstract

A synthetic decapeptide gonadotrophin releasinghormone (GnRH)5 was used to induce ovulation in PMSG-primed, prepuberal gilts weighing 55 to 75 kilograms. Five of 10 animals injected with 1.0 mg GnRH ovulated within 48 hr. after the injection. However, single injectionsof 0.5 mg or less GnRH failed to induce ovulation. The route of GnRH administration, intravenous or intramuscular, did not appear to influence the rate of ovulation or number of gilts ovulating. GnRH-treated gilts that ovulated showed a peak serum LH concentration of 1.7 to 3.6 ng/ml within 24 hr. of treatment.

Footnotes

1 The research was supported by Q.A.R.C. Grant McA-66-263 and by USPHS Research Grant HD 00739 from the National Institute of Child Health and Development. The authors gratefully acknowledge Mr. Jan Pika and Mr. P. Dumas for assistance during surgery and Mr. W. Wilfinger and Mrs. M. Dersookian for assistance with the radioimmunoassay.

2 Department of Animal Science, Macdonald Campus of McGill University, Ste. Anne de Bellevue, P. Q. 800, Canada.

3 Animal Health Division, Ayerst Research Laboratories, Chazy, New York, U.S.A.

4 Department of Zoology, University of Maryland, College Park, Maryland, U.S.A.






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Copyright © 1973 by the American Society of Animal Science.