J. Anim Sci.
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J. Anim Sci. 1972. 35:1201-1205.
© 1972 American Society of Animal Science
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Influence of Orally Administered Porcine Immunoglobulins on Survival and Performance of Newborn Colostrum-Deprived Pigs1

A. Scoot2, B. D. Owen2 and J. L. Agar3

University of Saskatchewan, Saskatoon, Canada

Abstract

Three experiments were conducted to evaluate, as an additive to milk replacers for colostrum-deprived pigs, a crude porcine immunoglobulin fraction prepared by ammonium sulfate fractionation of abbatoir blood serum. Six pigs per treatment were employed in experiments 1 and 2, and eight pigs per treatment in experiment 3. Allotment was on a littermate basis. When immunoglobulins were fed for 10 days postpartum, survival rates of pigs reared in a non-isolated environment were 83%, 83% and 75% in experiments 1, 2 and 3, respectively, and did not differ significantly from sow reared positive control pigs. Corresponding survival rates of negative control pigs (0%, 33% and 25%) were significantly lower in all cases. Slightly superior performance (88% vs. 75% survival) was obtained when the immunoglobulins were retained in the diet for 21 days. Levels of 10 g immunoglobulins per kilogram live weight on day 1, followed by 2 g per kilogram live weight daily were apparently as effective as 15 g followed by 5 grams. The use of unfractionated porcine blood serum as a source of immunoglobulins proved impractical.

Footnotes

1 The cooperation of Intercontinental Packers Ltd. and Federated Cooperatives Ltd., Saskatoon, and the financial assistance provided by National Research Council (Canada) are gratefully acknowledged. Technical advice and assistance provided by Drs. N. O. Nielsen, H. B. Schiefer and O. M. Radostits, Western College of Veterinary Medicine, Saskatoon, is appreciated.

2 Department of Animal Science.

3 Western College of Veterinary Medicine. Present address: Provincial Veterinary Laboratory. University of Manitoba, Winnipeg.






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