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University of Manitoba, Winnipeg 3, Canada2, 3,
Abstract
Adult female rats were maintained for 20 days on 100% or 50% of ad libitum feed intake or 50% ad libitum feed intake plus powdered glucose ad libitum. Body, pituitary and ovarian weights were reduced in animals on restricted feed intake while the same treatment plus glucose supplementation resulted in body and organ weights similar to full-fed animals (feed treatment, P<.01). The mean plasma LH concentration in rats on restricted feed intake was lower (P<.01) than that of full-fed rats or rats on restricted feed plus supplemental glucose. Restricted feeding with glucose supplementation resulted in a mean plasma LH concentration similar to that of full-fed controls. Anterior pituitary LH concentration was not significantly affected by feed level.
1 Supported in part by M.R.C. Canada Grant MA-4454 and a grant from the National Research Council of Canada (A-6248).
3 The author expresses appreciation to Dr. G. D. Niswender, University of Michigan for providing the anti-ovine LH serum, Dr. L. E. Reichert, Jr., Emory University for supplying the purified ovine LH for labelling and the Endocrine Study Section, NIH for supplying the NIH-LH-S14.
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