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Extraction of an Ulcer-Preventing Principle from Oat Hulls¹

Purdue University, Lafayette, Indiana 47097

Abstract

Polar and nonpolar extracts of oat hulls were prepared using conventional extraction procedures resulting in the formation of extracts of various composition. These extracts were investigated in swine for ulcer preventing properties. The polar (alcohol) extract from oat hulls was found to exert a significant protective effect for swine maintained on an ulcer-ogenic diet consisting mainly of gelatinized corn. The alcohol extract was also found to be a potent inhibitor of gastric acid secretion in the pig.

¹ Department of Animal Sciences Journal Paper No. 4082. Purdue University Agricultural Experiment Station. Research supported in part under Grant No. ES00071, U. S. Public Health Service.

² The data from thesis submitted to the Graduate School, Purdue University, in partial fulfillment of the requirements for the degree of Doctor of Philosophy.

³ Head, Pharmacology and Toxicology.

⁴ Professor of Animal Sciences.

⁵ Assistant Professor, Veterinary Clinics.