J. Anim Sci.
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J. Anim Sci. 1971. 32:1-9.
© 1971 American Society of Animal Science
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Chromosomal Aberrations in Cultured Porcine Fibroblasts after X-Irradiation of Male Progenitors1, 2,

D. L. Zartman3, N. S. Fechheimer and L. N. Baker4

Ohio State University, Columbus 43210

Abstract

ENVIRONMENTAL pollution is a matter of utmost importance to everyone. Probably, the most devastating of its prospective effects is the long-term damage to man and his food sources. Radiation is one of the pollutants at hand.

It is well known that radiation can cause chromosomal aberrations. The extent of the damage increases as the dose level and/or dose application rate increase. It is not known how much damage of this nature is transmissible to daughter cells or offspring of affected animals after a time lapse. Also, the degree to which cytoplasmic elements altered by irradiation can influence future cells and offspring is unknown.

This project was designed as part of a larger effort to determine the transmissible effects of X-irradiation on domestic animals and man. The pig was chosen as a representative animal. Of especial concern to the investigators in this study was the detection of transmitted effects on chromosomal aberrations due to X-irradiation of sires' gonads.

Footnotes

1 This work has received assistance from contract AT (11-1)-707 with the Atomic Energy Commission.

2 The authors wish to acknowledge the technical assistance of Quentin Preston, W. R. Harvey and the Ohio State University computer center.

3 Present address: Dairy Department, New Mexico State University, Las Cruces. 88001.

4 Present address: New York Blood Center, 310 East 67 Street, New York, New York 10021.






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Copyright © 1971 by the American Society of Animal Science.