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Effect of Poloxalene on Performance of Calves and Lambs^{1, 2,}

Iowa State University, Ames

Abstract

EXPERIMENTS by Bartley (1965), Bartley et al. (1965), Stiles et al. (1967) and Foote et al. (1968) have established poloxalene, a polyoxypropylene polyoxyethylene block polymer, as a highly effective legume bloat preventive for cattle. Lippke, Vetter and Jacobson (1969) found a somewhat lower efficacy for sheep.

Several experiments have been reported ascertaining the absence of undesirable sideeffects from feeding poloxalene (Helmet, Bartley and Meyer, 1965; Leaf, Wolf and Calendra, 1966; Meyer, Helmet and Bartley, 1965).

The work reported here was conducted to determine the effect of poloxalene on growth and digestibility when fed at recommended or high levels to calves and lambs.

Experimental Procedure

Trial I. Holstein calves (18 males and 18 females) were used to determine the effect of feeding 1 g or 4 g of poloxalene per 45.4 kg body weight daily on growth from 6 to 26 weeks of age. Calves were assigned to replicates within sex as they were born and were randomly assigned to treatment groups (control, 1-g or 4-g) within each replication.

¹ Supported in part by a grant from Smith Kline and French Laboratories, Philadelphia.

² Journal Paper No. J-6440 of the Iowa Agriculture and Home Economic Experiment Station, Ames. Project No. 1267.

³ Present address: Texas Agricultural Experiment Station, Angleton.

⁴ The authors gratefully acknowledge the assistance of Dr. D. K. Hotchkiss and Miss Leah Bimblich in statistical evaluation of the growth trial data.