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Biological Responses to Antibacterial Feed Additives in Diets of Meat Producing Animals¹

University of Florida², Gainesville

Abstract

In this report, an attempt has been made to document with meaningful examples the basic principles underlying feed additive usage in the production of meat animals. Three possible modes of action were presented: metabolic effect, nutrient sparing effect and disease control effect. All three were well supported by literature citations. It is evident that much interplay exists among the modes of action. However, in the final analysis, the evidence indicates that disease control, in its many and varied facets, is the overriding factor. Indeed, it is doubtful that any response of practical consequence would be obtained from antibacterial feed additives if sub-clinical and non-specific diseases were non-existent. Thus, it appears that the wise use of presently available compounds and others to come depends on more specialized application in keeping with a broadening understanding of disease stress in our animals.

Land grant institution personnel must continue to contribute effectively in this area of livestock nutrition and management. It is true that much of the glamour has subsided, but many important questions remain unanswered. The impact of antibacterial feed additives on livestock production has been phenomenal. We must continue to help direct and maintain proper perspective in this significant area. To do this we must conduct feeding trials and laboratory experiments and generally maintain a viable interest in all phases of feed additive research and application.

¹ Invitational paper presented at the Drugs and Feed Additives Symposium, 61st Annual Meeting of the American Society of Animal Science, August 3 to 6, 1969, Purdue University.

² Florida Agricultural Experiment Stations Journal Series No. 3583.