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University of Minnesota, St. Paul
Abstract
Concentrations of free ammo acids in the plasma are influenced by dietary supply and availability, rate of absorption from the gastrointestinal tract, withdrawal from the plasma for protein synthesis as influenced by growth and development, tissue protein catabolism in times of fast, amino acid imbalance and time post-feeding at which samples are collected. It appears essential to know the effect of fasting prior to time of withdrawal of blood samples on free amino acid patterns. If concentrations of plasma free amino acids are to provide meaningful information about protein in the diet, blood samples should ideally be obtained at a time that will reflect differences due to source and level of dietary protein, intakes of amino acids and availability of amino acids. Also, the plethora of free amino acids resulting from rapid influx from the small intestine should not mask the response to be measured.
1 Paper 7198, Scientific Journal Series of the Minnesota Agricultural Experiment Station.
2 Appreciation is expressed to Dr. I. E. Liener Department of Biochemistry, for determination of acid hydrolystates of liver protein.
3 Present address: School of Home Economics, University of Missouri, Columbia.
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