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Effect of Vitamin E and Selenium on Blood Composition of the Young Pig¹

Iowa Agriculture and Home Economics Experiment Station,² Ames

Abstract

Two experiments were conducted with young swine to study the effect of supplementing diets with vitamin E and selenium. Pigs fed the dystrogenic diets had elevated serum glutamic oxaloacetic transaminase (SGOT), serum glutamic-pyruvic transaminase (SGPT) and serum lactic acid dehydrogenase (LDH) activities indicating that these enzymes may be of value in diagnosing nutritional muscular dystrophy. The supplementation of selenium to the dystrogenic diets prevented increases in SGOT and SGPT. Supplemental selenium decreased, but did not completely suppress, the elevation of LDH activity. The activity of all serum enzymes of pigs fed diets supplemented with vitamin E alone remained essentially the same as the enzyme activities in the blood of pigs fed both vitamin E and selenium. The addition of vitamin E to the dystrogenic diets significantly decreased serum potassium during the first 6 weeks of the experimental period. Selenium alone or in combination had no significant effect on serum sodium, urea nitrogen, hemoglobin or blood glucose.

¹ Journal Paper No. J-6415 of the Iowa Agriculture and Home Economics Experiment Station, Ames. Project No. 1512.

² Department of Animal Science.