J. Anim Sci.
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J. Anim Sci. 1970. 30:904-910.
© 1970 American Society of Animal Science
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Influence of Dietary Supplements of Vitamin D3 and Various Fats on Cholesterol and Fatty Acid Composition of the Blood and Body of Growing-Finishing Swine1

M. H. Jurgens2, E. R. Peo, Jr., P. E. Vipperman, Jr. and R. W. Mandigo3

Nebraska Agricultural Experiment Station, Lincoln

Abstract

Previous work at this station suggested that vitamin D2, when fed with or without dietary cholesterol, depressed blood cholesterol levels of swine (Jurgens, Peo and Vipperman, 1967) and rats (Jurgens, Blunn and Peo, 1968). While not proven to be the cause, blood cholesterol levels have been used as one of the main criteria to estimate the development of atherosclerosis in man (Rabinowitz, Meyerson and Wohl, 1960; Swell, Law and Treadwell, 1962). Several investigators have reported that supplementation of unsaturated fats (Ahrens et al., 1957; Okey and Lyman, 1957; Avigan and Steinberg, 1958; Peifer, 1966) and especially linoleic acid (Jagannathan, 1962; Swell et al., 1962), into the diet will reduce blood cholesterol levels. Thus, the present work was undertaken to study the effects of dietary supplements of vitamin Dg with either a highly unsaturated fat (safflower oil) or a highly saturated fat (coconut oil) on the cholesterol content of blood and the cholesterol and fatty acid composition of certain tissues of growing-finishing swine.

Footnotes

1 Published with the approval of the Director as Paper No. 2644, Journal Series, Nebr. Agr. Exp. Sta.

2 Present address: Iowa State University, Ames.

3 Department of Animal Science. Acknowledgement is made to John Welch for assistance in development of certain of the laboratory procedures and to P. J. Cunningham and associates lor care of the experimental animals.






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