J. Anim Sci.
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J. Anim Sci. 1970. 30:791-794.
© 1970 American Society of Animal Science
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Control of Estrus and Ovulation in the Pig by ICI 33828 and Gonadotropins1

S. K. Webel, J. B. Peters and L. L. Anderson

Iowa State University, Ames2

Abstract

The objectives of this study were to control the time of estrus and the ovulation rate in the pig for experiments dealing with surgical transfer of ova and blastocysts. Estrous cycles were controlled in 166 cycling gilts by feeding ICI 33828 for 20 days to suppress estrus. A dose of 1,000, 1,250 or 1,500 IU of pregnant mare serum (PMS) the day ICI 33828 was withdrawn and 850 IU human chorionic gonadotropin (HCG) 96 hr. later stimulated and controlled ovulation rate. Ninety percent of the gilts exhibited estrus in a 2-day period, either on the day of HCG injection or the following day. The conception rate was 91% as determined by microscopic examination of ova in 68 gilts on days 4 to 8. Ovulation rates averaged 15.5, 22.5 and 20.3 for 1,000, 1,250 and 1,500 IU PMS, respectively. The ovulation rate in animals in a control group not receiving ICI 33828 or PMS averaged 11.7. The month in which estrus occurred, holding the effect due to level of PMS constant, and the average maximum daily temperature during the 4 days before ovulation significantly affected ovulation rate.

Footnotes

1 This study was supported, in part, by Grants HD 01168-10 and HD 00184-02 from the National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland. This is Journal Paper No. J-6380 of the Iowa Agriculture and Home Economics Experiment Station, Ames, Iowa. Projects No. 1325 and 1712. The authors thank Dr. R. J. Nuttall, Ayerst Laboratories, New York, N. Y., for supplies of ICI 33838; Dr. J. B. Jewell, Ayerst Laboratories, New York, N. Y., for pregnant mare serum gonadotropin (EQUINEX); and Dr. E. R. Symonds, E. R. Squibb & Sons, East Brunswick, N. J., for chorionic gonadotropin (FOLLUTEIN). Thanks are also expressed to Dr. D. F. Cox, Department of Statistics, for advice on statistical analyses.

2 Department of Animal Science.






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Copyright © 1970 by the American Society of Animal Science.