J. Anim Sci.
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J. Anim Sci. 1970. 30:409-411.
© 1970 American Society of Animal Science
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Effects of Prostaglandins E1 and F1{alpha} Upon Carbohydrate Metabolism of Ejaculated and Epididymal Ram Spermatozoa In Vitro

J. Thomas Pento1, Richard J. Cenedella and E. K. Inskeep2

West Virginia University Medical Center,3, Morgantown

Abstract

The effects of prostaglandins E1 and F1{alpha} on oxygen consumption and glucose metabolism of ejaculated and epididymal sperm cells were studied in vitro. Samples were taken from four rams for each experiment. Prostaglandins had no effect on ejaculated sperm. Both PGE1 and PGFla increased (P<.01 and P<.05, respectively) oxidation of glucose to CO2 by epididymal sperm. PGF1{alpha} reduced oxygen consumption by epididymal sperm (P<.05) while PGE1 had no effect.

Footnotes

1 Present address: Space Sciences Research Center, Columbia, Missouri 65201.

2 Division of Animal and Veterinary Science.

3 Department of Pharmacology.






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