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Metabolic Effects of Growth Hormone and Diethylstilbestrol in Lambs. II. Effects of Daily Ovine Growth Hormone¹ Injections on Plasma Metabolites and Nitrogen-Retention in Fed Lambs^{,2, 3,}

University of Illinois, Urbana-Champaign⁶

Abstract

Studies were conducted to evaluate the effects of daily injections of ovine GH in fed sheep on plasma levels of NEFA, glucose, insulin, PUN and FAA-N. The effects of treatment on nitrogen balance were also observed. It was noted that GH treatment resuited in increased levels of plasma NEFA, glucose and insulin and a decrease in PUN. No detectable effect was noted on plasma FAA-N. Nitrogen-retention was almost doubled during GH treatment.

These effects of GH treatment are in agreement with results reported by others in both ruminant and nonruminant species.

¹ Ovine growth hormone (S9) courtesy Dr. Morris Graff, Endocrinology Study Section, National Institutes of Health, Bethesda, Maryland.

² Supported in part by federal funds Hatch 20–346 and by grants-in-aid from Moorman Manufacturing Company, Quincy, Illinois.

³ Data taken from thesis submitted to the Graduate College of the University of Illinois by the senior author in partial fulfillment of the requirements of the Ph.D. degree.

⁴ Present address: Medical College, University of Michigan, Ann Arbor.

⁵ NIH Contract USPH GM00653.

⁶ Animal Science Department.