J. Anim Sci.
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J. Anim Sci. 1970. 30:207-213.
© 1970 American Society of Animal Science
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Substances Affecting Fat Mobilization in the Urine of Fasting Sheep1,2,

R. W. Farmer3, E. C. Leffel3 and S. Lakshmanan4

University of Maryland, College Park

Abstract

Studies of the urinary execretion of substances which affect fat mobilization were conducted. The only adipokinetic active substance was of a low molecular weight (<385) and reacted positively to qualitative chemical tests for catecholamines. A net antiadipokinetic or insulin-like activity was found more frequently in the urine. The presence of this activity was dependent upon a prior feeding of a diet containing 50% concentrate. The antiadipokinetic substance (s) were of a molecular size smaller than insulin and larger than Evans blue (985). The significance of these observations is discussed.

Footnotes

1 This work constituted a portion of the Ph.D. Dissertation of R. W. Farmer, Texas Research Institute of Mental Sciences, 1300 Moursund Avenue, Houston, Texas.

2 Scientific Article No. A1388, Contribution No. 3985 of the Maryland Agricultural Experiment Station, Department of Animal Science.

3 Department of Animal Science.

4 Department of Chemistry.






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Copyright © 1970 by the American Society of Animal Science.