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Discussion

University of Illinois, Urbana

B. Cook

Abstract

It is indeed an honor for me to discuss the excellent paper presented by Dr. Denamur. The many experiments conducted in his laboratory have contributed greatly to our knowledge of the factors affecting luteal function in the ewe. I want to take this opportunity to present part of our work so that we might clarify some of the apparent differences between our data and those of Dr. Denamur and his colleagues.

The first experiment that I would like to discuss was conducted to determine if pituitary support is in fact necessary for the normal formation of corpora lutea in the ewe. The animals were laparotomized and hypophysectomized on the day of ovulation (day 1) and the CL were examined again on day 8. Appropriate control animals were laparotomized on day 1 and the CL were removed on day 8. This procedure was carried out in both cyclic and anestous animals.

¹ The studies reported here were supported in part by Grant AM 06976 from the National Institutes of Health. The gonadotrophic hormones used in these studies were generously supplied by Drs. W. F. White and R. E. Mauer of Abbott Laboratories, North Chicago, Illinois.