J. Anim Sci.
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J. Anim Sci. 1968. 27:1383-1386.
© 1968 American Society of Animal Science

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Effects of Exogenous Progesterone and Hysterectomy on Corpora Lutea in Ewes1, 3,

C. O. Woody, O. J. Ginther2 and A. L. Pope

University of Wisconsin, Madison

Abstract

The effects of hysterectomy and exogenous progesterone on estrous cycle length and on CL weight were studied in breeding season ewes. Estrous cycle length tended to be reduced in intact progesterone treated ewes. Hysterectomy prevented the recurrence of estrus for 60 days in six of six hysterectomized, non-progesterone treated ewes and in five of six hysterectomized, progesterone treated ewes. CL weight at day 11 was reduced by progesterone treatment (P<.005) but this reduction was less in hysterectomized ewes than intact ewes as indicated by the interaction of progesterone and hysterectomy (P<.01).

Further, the effects of hysterectomy and exogenous progesterone on weight of CL induced in anestrous ewes were studied. Average CL weight was decreased by progesterone (P<.05) and increased by hysterectomy (P<.005). Progesterone reduced average CL weight only in the intact ewes as is indicated by the presence of an interaction (P<.05).


Footnotes

1 Published with the approval of the director of the Agricultural Experiment Station, Paper No. 1170 from the Genetics Laboratory and No. 491 from the Department of Meat and Animal Science. This work was done under a cooperative agreement between the Wisconsin Agricultural Experiment Station and the Dairy Cattle Research Branch, U.S.D.A. It was supported in part by the Branch and also by Public Health Service Training Grant No. 5 TO1 HD00104–03, from the National Institutes of Child Health and Human Development, and the Ford Foundation, Grant No. 63-505.

3 The advice and support of Dr. L. E. Casida is gratefully acknowledged.

2 Supported by Public Health Service postdoctoral fellowship, No. 1 F2 HD-23, 054-01, from the National Institute of Child Health and Human Development. Present address: Department of Veterinary Science, University of Wisconsin, Madison.







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Copyright © 1968 by the American Society of Animal Science.