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Effect of Administration Route upon Iron-59 Retention in Miniature Swine as Measured in a 2-pi Liquid Scintillation Whole Body Counter^{1, 2,}

University of Missouri, Columbia

Abstract

Iron retention, as affected by route of administration, was studied using 3-wk.-old Hormel strain miniature swine. Iron-59 retention was measured, for a 28-day period, using the whole body counting technique. The pigs retained approximately 75% of the injected iron; however, there was no significant effect due to route of injection.

¹ This study was supported in part by the Sinclair Comparative Medicine Farm for studies of Aging and Chronic Diseases (USPHS Grant No. FR 00285-01).

² The authors acknowledge the technical assistance of D. R. Clark.

³ Departments of Veterinary Physiology and Pharmacology and Medical Biochemistry.

⁴ Department of Veterinary Microbiology.

⁵ Low Level Radiation Laboratory, Whole Body Counter, Agricultural Experiment Station.