J. Anim Sci.
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J. Anim Sci. 1967. 26:1113-1115.
© 1967 American Society of Animal Science
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Effects of Exogenous Progesterone on Corpora Lutea Induced in Anestrous Ewes1

C. O. Woody, O. J. Ginther and A. L. Pope2

University of Wisconsin, Madison

Abstract

The effects of exogenous progesterone on corpora lutea induced in anestrous ewes were studied in four experimental groups: (1) no progesterone, (2) 25 mg. progesterone per day for 6 days prior to ovulation, (3) 25 mg. progesterone per day for 6 days beginning on the expected day of ovulation and (4) 25 mg. progesterone per day for 12 days beginning 6 days prior to ovulation. The ewes were killed 6 days after the expected day of ovulation. The average corpus luteum weight and the number of ewes for these groups were, respectively: (1) 260.6 mg., 14 ewes; (2) 117.5 mg., 14 ewes; (3) 329.5 mg., 15 ewes; (4) 90.4 mg., 15 ewes. Progesterone injections beginning the expected day of ovulation did not reduce corpus luteum weight. Progesterone injections prior to the time of ovulation resulted in smaller (P<.01) corpora lutea whether or not the injections were continued after the time of ovulation.

Footnotes

1 Published with the Approval of the Director of the Agricultural Experiment Station, Paper No. 1114 From The Genetics Laboratory and No. 471 from the Department of Meat and Animal Science. This Work was Done Under a Cooperative agreement Between the Wisconsin Agricultural Experiment Station and the Dairy Cattle Research Branch, U.S.D.A. It was Supported in Part by the Branch and in Part by Public Health Service Training Grant No. 5 T01HD00104-02, from the National Institute of Child Health and Human Development, and funds from the Ford Foundation.

2 The Advice of Dr. L. E. Casida, Especially in Planning the experiments, is gratefully acknowledged.






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Copyright © 1967 by the American Society of Animal Science.