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Uterine Metabolic Status during Pregnancy and Litter Size in Rats^{1, 2,}

University of Nebraska, Lincoln

Abstract

Uterine metabolic status measured by determining TTC reduction rate of the tissue in pregnant rats was studied in relation to litter size. Uterine TTC reaction at day 4 of pregnancy was related curvilinearly with litter size at term; average uterine metabolic levels were associated with larger litter size than were very low or very high levels. Uterine reaction determined at day 8 was almost linearly associated with litter size: the lower the value, the larger the liter size. At day 12 of pregnancy uterine TTC reaction rate was again curvilinearly related to litter size; average uterine TTC reaction levels were associated with larger litters, and both low and high values were associated with smaller litters.

¹ This work supported by U.S.P.H. Grant GM-11129.

² Published with the approval of the Director as Paper No. 1773, Journal Series, Nebraska Agricultural Experiement Station, Lincoln.