J. Anim Sci.
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J. Anim Sci. 1963. 22:1046-1050.
© 1963 American Society of Animal Science

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Muscular Dystrophy in Early Weaned Lambs1

R. F. Borgman2, R. L. Edwards3, W. C. Godley3 and S. L. Moore3

Clemson College, Clemson, South Carolina

Abstract

Lambs weaned at 30 to 35 lb. and then fed pelleted dehydrated Coastal Bermuda grass and a concentrate in drylot for 14 weeks developed a muscular dystrophy, as indicated by post-mortem examinations, serum glutamic oxaloacetic transaminase levels, weight gains, and visual ratings. The mortality and severity of the disease were increased when the lambs were turned on pasture for an additional 10 weeks. No differences were noted as to sex. Neither vitamin E, sodium selenate, or a combination of these affected the course of the disease in the doses employed. Higher dosages may have been desirable and are being employedin current studies. Both dried skim milk and dried whole milk retarded the dystrophy, and dried whole milk seemed superior in this respect. The etiology of the disease syndrome observed here may be other than a vitamin E and/or selenium deficiency or may be an interference of the metabolism of vitamin E and/or selenium.


Footnotes

1 Technical Contribution No. 416, South Carolina Agricultural Experiment Station. Published by permission of the Director. This investigation was supported in part by a PHS grant. No. A-4 273, from the National Institute of Arthritis and Metabolic Diseases, Public Health Service. Thanks are due to R. A. Jameson and R. L. Wilson for technical assistance, and to Merck & Co. of Rahway, New Jersey, for donating the a-tocopheryl acetate used in this study.

2 From the Department of Food Technology and Human Nutrition.

3 From the Department of Animal Science.







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Copyright © 1963 by the American Society of Animal Science.