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Effect of Repeated Injections of Iron-Dextran upon Blood Hemoglobin and Hematocrit and upon the Iron and Myoglobin Concentration and Color of the Semimembranosus Muscle of Swine¹

Michigan Agricultural Experiment Station, East Lansing

Abstract

A study was conducted to determine the effect of repeated intra-muscular injections of iron-dextran in swine. Two experimental and two control animals were slaughtered at 7, 9, 16 and 22 weeks of age, the experimental animals having received a total of 150, 450, 1100 and 1650 mg. of iron, respectively. Hemoglobin and hematocrits increased with repeated injections through 9 weeks of age. At 16 and 22 weeks of age the injected pigs had lower hemoglobin and hematocrits than the control pigs. Repeated injections of iron apparently did not affect the myoglobin concentration or surface color of thsemimembranosu muscle. However, the external ham fat of animals that had received 1650 mg. of iron had a slight rusty color. Muscle iron concentration was significantly higher in the experimental animals than in the controls at 22 weeks of age; however, the injected ham contained, on the average, less total iron than the non-injected ham.

¹ Journal Article 2676 Michigan Agricultural Experiment Station, East Lansing.

² The authors wish to acknowledge the assistance of C. L. Zutaut in performing the muscle iron determinations.

³ Armidexa^–75, manufactured by Armour and Company, Kankakee, Illinois.

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