Am. Soc. Anim. Prod.
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Some Practical Applications of Endocrinology to Animal Husbandry

S. A. Asdell*

New York State College of Agriculture

Abstract

I. Hormone treatment in cases of sterility in dairy cattle.

Recent developments in the field of sex hormones have given some indications of the mode of action of the various substances from the anterior pituitary and the ovary. Their orderly interaction gives us normal reproduction. If, for some reason the sequence of events is altered, either by inco-ordination or by pathology, abnormalities of reproduction result. It is logical, therefore, to assume that the abnormal reproductive cycles may be reinforced by the administration of hormones, or that by the use of these substances the organism may be aided in its fight against pathological influences. Accordingly, as opportunity has offered, attempts have been made to use the newer weapons at our disposal. The animals treated have all withstood prolonged efforts by the usual therapeutic means to overcome their sterility. They may therefore be regarded as the hopelessly sterile residue of a large herd.

  1. Cows with normal or irregular oestrus cycles, which breed, but which do not conceive. In these cows large doses of oestrone benzoate (Progynon B, donated by Schering Corporation), 50,000 international units or more, were injected subcutaneously the day before the cow was expected to be in heat. In some cases the cows came in heat more violently than usual, but in some no response was observed. Of the eight cows injected, two became pregnant, one immediately, and one after a short delay. A mare similarly treated has also become pregnant.

Footnotes

* With the cooperation of H. J. Brooks and G. H. Ellis, New York State College of Agriculture, and M. G. Fincher, New York State Veterinary College.






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