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The Relation of the Anterior Pituitary to Lactation^*

University of Missouri

Abstract

Correlated with the approach of puberty and the gradual development of the ovary, the first marked extra-uterine growth of the mammary apparatus begins. However, in most mammals the glands are still in a rather primitive condition even though they may have passed through a number of estrus cycles. The glands at this time are usually characterized by the presence of a cistern and duct system spreading out from the base of the teat, but with either the entire absence of the lobules and alveoli or at most but slight development of the secretory parts of the gland.

When the estrus cycle is of great length with a considerable period covered by the luteal phase of the cycle, or when the luteal phase of the cycle is extended by the production of the so-called "pseudo-pregnant" condition, the gland then approaches in appearance that of the pregnant gland with marked lobule development.

^* These studies are being aided in part by a grant from the Committee on Grants-in-Aid of the National Research Council.