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Sustained Prevention of Bloat by Feeding Antibiotics in Rotation or in Combination¹

Iowa State University, Ames

Abstract

During the 1959 pasture season three groups of dairy and beef cattle, approximately equal in bloating potential, grazed bloat-provoking alfalfa pasture. Each group received several antibiotics in combination or in rotation or served as control. Results indicated that the period of effectiveness of antibiotics can be extended considerably by feeding several different antibiotics in rotation or by feeding them in combinations. Those found particularly effective were penicillin, erythromycin and tylosin; chloramphenicol, novobiocin and oxytetracycline were less effective. Neomycin and Spontin were of questionable value. Limited data indicated that vancomycin may, under some conditions, increase bloat. Penicillin and erythromycin were more effective for a longer period of time when fed together than when fed in rotation.

¹ Journal Paper No. J-3768 of the Iowa Agricultural and Home Economics Experiment Station, Ames, Iowa. Project No. 1267. Supported in part by funds provided by Regional Project NC-27.

² Present address: Dawe's Laboratories, Inc., Chicago, Illinois.

³ Present address: Department of Animal Industries, University of Connecticut, Storrs.