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Effect of Feeding Different Tranquilizers in Combination with Implanted Diethylstilbestrol or Oral Antibiotic on Fattening Beef Steers^{1, 2,}

Purdue University, Agricultural Experiment Station, Lafayette, Indiana

Abstract

The results from three experiments designed to study the value of adding tranquilizers to the rations of fattening beef steers are reported. One level of hydroxyzine (2.5 mg. per head daily) was effective in stimulating the rate of gain of beef steers in one experiment in which steers were implanted with 36 mg. diethylstilbestrol and were being fed 80 mg. oxytetracycline per day. Except for this, no tranquilizer, at the level fed (Rauwolfia vomitoria, 25 mg. per day; reserpine, 60 mcg., 1 mg. or 2 mg.; hydroxyzine, 1.25 mg., 2.5 mg. or 5.0 mg.; trifluomeprazine, 2.5 mg., 5.0 mg. or 10 mg.), resulted in increased rate of gain, improved feed efficiency or improved carcass quality.

No consistent synergism was apparent between the tranquilizers tested and implanted diethylstilbestrol, oral oxytetracycline or diethylstilbestrol and oxytetracycline in combination.

¹ Contribution from the Department of Animal Science, Journal Paper No. 1512.

² Supported in part by grants from Chas. Pfizer and Co., Terre Haute, Indiana; Ciba Pharmaceuticals, Inc., Summit, New Jersey; and Smith, Kline and French Laboratories, Philadelphia, Pennsylvania.