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The Effect of Tranquilizers, Diethylstilbestrol and Oxytetracycline Alone and in Combination on Performance of Steers

Chas. Pfizer & Co., Inc., Agri. Res. & Development Center, Terre Haute, Indiana

Abstract

The tranquilizing drug hydroxyzine, which was evaluated at low levels alone or in combination with stilbestrol or oxytetracycline in three steer-fattening experiments produced increases ranging from 6 to 12% in average daily gain and improvement of 4.8 to 9.2% in feed efficiency. Ground Rauwolfia vomitoria root produced smaller growth and feed efficiency responses in one trial and 11.3% and 3.5%, respectively, in another. Reserpine tested in one trial enhanced average daily gain by 6.2% and feed efficiency by 5.2%. There was no indication of lowered carcass quality and in several instances the tranquilizers appeared to improve carcass grade. The use of nutritional levels of tranquilizers was not accompanied by gross evidence of sedation.