J. Anim Sci.
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J. Anim Sci. 1958. 17:343-352.
© 1958 American Society of Animal Science

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Effects of Orally Administered Stilbestrol upon Growth and upon Calcium and Phosphorus Metabolism in Lambs1

Joseph D. Shroder2 and Sam L. Hansard3

University of Tennessee—Atomic Energy Commission Agricultural Research Program

Abstract

The response of lambs to stilbestrol feeding was measured using autoradiograph techniques as an indicator for bone growth. In addition concurrent chemical and radiochemical blood and balance studies were made with growing lambs to determine the effects of orally administered stilbestrol upon calcium and phosphorus metabolism. Results of these investigations indicated that in the ruminant animal the primary effect of stilbestrol administration was that of growth stimulation. This was manifested by a reduction in fecal endogenous calcium of approximately 20% with little apparent influence upon calcium absorption from the gastrointestinal tract. Phosphorus absorption was increased, but fecal endogenous phosphorus was only slightly decreased by the treatment.


Footnotes

1 A portion of a dissertation presented by the senior author to the Graduate School, Oklahoma State University, in partial fulfillment of requirements for the degree of Doctor of Philosophy.

2 Formerly Graduate Fellow, Oak Ridge Institute of Nuclear Studies, Oak Ridge, Tennessee. Present address: Department of Animal Husbandry, Iowa State College.

3 Present address: Department of Animal Industry, Louisiana State University. This manuscript is published with the approval of the Director of the University of Tennessee Agricultural Experiment Station, Knoxville, Tennessee. The radioactive materials used in this work were obtained from the Oak Ridge National Laboratory on allocation from the United States Atomic Energy Commission. This work was completed under Contract No. AT-40-1-GEN-242 between the University of Tennessee, College of Agriculture and the Atomic Energy Commission.







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Copyright © 1958 by the American Society of Animal Science.