J. Anim Sci.
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J. Anim Sci. 1958. 17:68-72.
© 1958 American Society of Animal Science
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A Study of Xanthurenic Acid Excretion by Swine1

H. H. Draper, R. Hironaka and A. H. Jensen

University of Illinois2

Abstract

A study is reported of the urinary xanthurenic acid excretion of pregnant and non-pregnant gilts and sows, and of growing pigs. No evidence was found of a derangement of tryptophan or pyridoxine metabolism associated with pregnancy, such as that reported for some human subjects. Administration of DL-tryptophan resulted in an elevation of xanthurenic acid excretion which was unaffected by simultaneous administration of pyridoxine. Insulin had no effect on the excretion of xanthurenic acid, indicating that the substantial amounts of this compound found in the urine are not associated with the poor glucose tolerance which is alleged to be characteristic of the species.

Footnotes

1 The authors gratefully acknowledge the gift of DL-tryptophan and a sample of xanthurenic acid from Merck-Sharp & Dohme, Inc., Rahway, N. J., and of vitamins and Aureomycin from American Cyanamid Company, Pearl River, N. Y.

2 Department of Animal Science, Urbana, Illinois.






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Copyright © 1958 by the American Society of Animal Science.