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Serum Transaminase in White Muscle Disease^1,2,

University of Nevada, Reno³

Abstract

Serum glutamic-oxalacetic transaminase activity increased markedly in lambs and calves with white muscle disease (muscular dystrophy). The serum transaminase activity appears to be proportional to the extent of muscle damage. This increase may permit the objective diagnosis of white muscle disease without sacrifice of the animal.

¹ The authors wish to gratefully acknowledge K. L. Kuttler and D. W. Marble, Department of Veterinary Science, University of Nevada, for providing blood samples from normal and pathological animals, and for post-mortem diagnosis of white muscle disease. Grateful acknowledgement is also made to R. M. Pearson for assistance with the analytical work, and to Miss Margaret Robinson, Washoe Medical Center, for assistance in setting up and standardizing the procedure.

² A report of this work was presented at the annual meeting of the Western Section of the American Society of Animal Production, July 14–17, 1957.

³ Department of Agricultural Chemistry.

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