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The Influence of Protein Content of the Diet and of Chlortetracycline and/or Vitamin B₁₂ Supplementation upon Performance of Growing-Fattening Pigs^1,2,

Nebraska Agricultural Experiment Station

Abstract

IN an early report on the use of APF (Animal Protein Factor) supplements in swine rations Cunha et al. (1950) suggested that the protein requirements of swine might need to be re-evaluated using adequate amounts of vitamin B₁₂, plus other factors present in Lederles' APF supplement. Jukes et al. (1950) showed that chlortetracycline (Aureomycin) was largely responsible for the increased rate of gain of growing swine fed this APF supplement.

It has since been reported by Catron and coworkers (1952) that corn-soybean oil meal type diets adequate in non-protein dietary factors and containing a 14-11-8 percent protein combination were equal to a 16-13-10 percent combination for pigs from weaning to 75, 75 to 150 and 150 to 200 lb. when chlortetracycline was added to the lower level protein combination. These workers and Burnside et al. (1954) suggested that antibiotic apparently effected a protein-sparing action with respect to the pigs' protein needs. Robison (1952), Bowland and McElroy (1952) and Botkin et al. (1951) have reported experiments in which lower protein diets supplemented with an antibiotic were equal or superior to higher protein diets without an antibiotic.

¹ Published with the approval of the Director as Paper No. 725, Journal Series.

² This work partially supported by grants-in-aid or contributions of investigational materials by Lederle Laboratories Division, American Cynamid Company, Pearl River, New York; Merck & Company, Inc., Rahway, New Jersey; and Swift & Company, Chicago, Illinois.

³ Acknowledgment is made to Mr. Alvah Markussen, Foreman, Swine Research Center, and his associates for their assistance.