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Response of Lambs Fed Varied Levels of Diethylstilbestrol ^1,,2

Iowa Agricultural Experiment Station³

Abstract

The feeding of approximately 2 mg. of diethylstilbestrol (stilbestrol) per wether lamb per day in connection with a fattening ration increased rates of gains approximately 22 percent over the controls. No consistant increase in feed consumption was noted with stilbestrol-fed lambs. At this level of supplementation stilbestrol had little or no effect upon carcass quality; however, at higher levels there was an apparent decrease in carcass quality. Higher levels of supplementation (3.6 mg. per lamb per day) in group feeding trials failed to promote as satisfactory rates of gain as did the lower levels. Close examination of supplemented lambs revealed certain changes in external appearance similar to those noted with stilbestrol implanted lambs. The changes were enlargement of the prepuce, mammary development and edema of the anal area. The degree of these conditions appeared to be associated with level of stilbestrol feeding. The severe toxicity symptoms noted with stilbestrol implanted lambs were not observed by oral administration of stilbestrol in these experiments.

¹ Journal paper No. J-2764 of the Iowa Agricultural Experiment Station, Ames, Iowa, Project No. 869.

² The ground corn cobs used in this study were supplied by John Clay Co., Kansas City, Missouri and the feeding fat by Wilson and Co., Cedar Rapids, Iowa. Carcass grade and yield on the group-fed animals was made possible through cooperation of Wilson and Co., Cedar Rapids, Iowa. Acknowledgment is made to Mr. Victor Applegate of the Ruminant Nutrition Laboratory for his assistance.

³ Ames, Iowa.