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Antibiotic Feeding for Prophylaxis of Experimentally Produced Swine Erysipelas¹

State College of Washington

Abstract

Swine erysipelas was produced experimentally in weanling pigs by the dermal scratch method. Typical symptoms and lesions of erysipelas were shown by the pigs following inoculation with Erysipelothrix rhusiopathiae.

Penicillin or oxytetracycline at the rate of 15 mg. per pound of feed had no effect on the symptoms or lesions of the erysipelas-infected pigs. Penicillin fed in a ration to pigs at a level of 40 mg. per pound of feed failed to inhibit the symptoms or lesions of erysipelas, as measured by skin changes and temperature levels. The penicillin-fed pigs gained an average of 1.62 lb. daily, while those on a penicillin-free ration gained only 1.52 lb. per pig daily. This difference was significant (P less than .05).

¹ Scientific Paper No. 1356, Washington Agricultural Experiment Stations, Pullman. Project No. 1067. Supported in part by a grant from the Eldridge and Mary Stuart Foundation. The authors are indebted to Chas. Pfizer & Co., Inc., for supplying the penicillin and Terramycin used in these experiments and for in vitrotesting of the organism against several antibiotics.

² Professor of Animal Husbandry, Professor and Chairman, Department of Veterinary Pathology, and Professor and Chairman, Department of Animal Husbandry, respectively.