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The Effect of Antibiotics on the Intestinal and Cecal Microflora of Baby Pigs Fed a "Synthetic Milk"

University of Illinois^,3

Abstract

A comparative study was made on the intestinal and cecal microbial population of 5-week-old pigs which had been raised from birth in the presence and absence of terramycin and whose gains had indicated a significant response to the antibiotic.

From the plate counts made of the organisms growing on four types of media including aerobic and anaerobic incubation, the data suggest that the effect of terramycin on the total numbers of microbes in all intestinal sections from the duodenum to the cecum is to increase their numbers about tenfold.

None of the various types of flora found in the gut of the basal animals was conspicuously absent from the contents of the gut of animals receiving the antibiotic.

¹ Present address: Botany Faculty, North Carolina State College, Raleigh, North Carolina.

² With the assistance of T. Folkerts, Elizabeth Schoen, Eva Cohn, and Margaret Keane.

³ Division of Animal Nutrition and Department of Bacteriology, Urbana.