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Urinary Calculi in Sheep¹

Washington Agricultural Experiment Station

Abstract

Data on the effect of high intake of CaCO₃, MgCO₃ and K₂HPO₄ on the blood and urine contents of calcium, phosphorus, magnesium, urine pH, urine total solids, urine volume and their possible relation to urinary calculi formation have been presented. Under the conditions of this experiment, supplementation with K₂HPO₄ was apparently the cause of the highest incidence of calculi. A vitamin A- or carotene-free diet does not seem to be involved in calculi formation. The rams that produced urine with the lowest total solids were the rams that had the highest incidence of calculi. In the lots where there was a high incidence of calculi, the rams had an increased rate of water consumption and an increased rate of urine excretion.

¹ Scientific Paper No. 1216, Washington Agricultural Experiment Stations, Pullman. Project No. 1001.

² Present address: Department of Animal Husbandry, Mississippi State College.

³ Assistant Animal Husbandman, Graduate Assistant, Assistant Animal Husbandman, and Animal Husbandman, respectively.

To be presented by E. D. Taysom as part of a thesis in partial fulfillment of the requirements for the Doctor of Philosophy degree from the State College of Washington.

This investigation was supported in part by funds provided for biological and medical research by the State of Washington Initiative Measure No. 171.

Appreciation is expressed to Dr. G. R. Spencer, Chairman, Department of Veterinary Hygiene and Pathology and his staff, College of Veterinary Medicine, State College of Washington, Pullman, for their excellent cooperation in autopsies and counsel during this study.