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The Supplementary Effects of Calcium Pantothenate and Aureomycin in a Low Protein Ration for Weaning Pigs¹

Michigan Agricultural Experiment Station

Abstract

Sixty 25-pound pigs were used to study the effect of aureomycin on the pantothenic acid requirement. A low protein basal ration (15.4 percent) containing 4.15 mg. of pantothenic acid per pound was used.

Five out of 10 pigs fed the basal ration developed symptoms of locomotor incoordination. When aureomycin was added (5 mg. per pound) to the basal ration, an equal number of pigs developed deficiency symptoms indicating no sparing action on the part of this antibiotic for pantothenic acid. However, the addition of calcium pantothenate at a level of 2 mg. per pound to the basal ration prevented all symptoms of deficiency from appearing.

Possible reasons for apparent variations in pantothenic acid requirement of pigs are discussed.

¹ Published with the approval of the Director of the Michigan Agricultural Experiment Station as Journal Article No. 1488.

² Departments of Agricultural Chemistry, Animal Husbandry and Animal Pathology, Michigan State College, East Lansing. This work was supported in part by a grant from Lederle Laboratories Division, American Cyanamid Co., Pearl River, New York.