J. Anim Sci.
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J. Anim Sci. 1953. 12:394-401.
© 1953 American Society of Animal Science
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The Effect of Methionine on the Tissue Distribution of Radioactive Cobalt Injected Intravenously into Dairy Calves1

Ray E. Ely2, K. M. Dunn3 and C. F. Huffman

Michigan Agricultural Experiment Station

C. L. Comar4 and George K. Davis

Florida Agricultural Experiment Station

Abstract

While intravenously administered methionine prevented the physiological symptoms observed when high doses of cobalt were administered intravenously, it did not alter the distribution of cobalt in the tissues investigated.

Toxic doses of cobalt administered intravenously are rapidly removed from the blood. The concentrations in the liver, kidney and lymph system remains relatively high for at least 12 hours following the intravenous administration of cobalt. The principle excretory pathways are apparently the kidney, liver and lymph system.

Footnotes

1 Published with the approval of the Director of the Michigan Agricultural Experiment Station as Journal Article No. 1396.

2 Present address: Bureau of Dairy Industry, U. S. Dept. of Agriculture, Washington, D. C.

3 Deceased.

4 Present address: UT-AEC Agricultural Res. Prog., Oak Ridge.






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Copyright © 1953 by the American Society of Animal Science.