J. Anim Sci.
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J. Anim Sci. 1952. 11:326-331.
© 1952 American Society of Animal Science

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Alleviation of Cobalt Toxicity in Calves by Methionine Administration1

K. M. Dunn, R. E. Ely3 and C. F. Huffman

Michigan State College4

Abstract

Calves were able to tolerate intravenous injections of small doses of cobalt without symptoms of toxicity.

Larger doses of cobalt sulfate (0.3 mg. of cobalt per pound of body weight or more) caused symptoms of toxicity which were lacrimation, salivation, dyspnea, incoordination, defecation and urination.

The injection of methionine previous to the injection of cobalt prevented or markedly reduced the severity of these toxicity symptoms.

The lethal dose of cobalt injected intravenously is more than 4 mg. per pound of body weight for the dairy calf.


Footnotes

1 Published with the approval of the director of the Agricultural Experiment Station as journal article No. 1291 (n.s.).

3 Present address: Bureau of Dairy Industry, USDA, Beltsville, Md.

4 Dairy Department, East Lansing, Michigan.







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