J. Anim Sci.
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J. Anim Sci. 1952. 11:273-281.
© 1952 American Society of Animal Science

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The Effect of Thyroid on Carotenoid Metabolism in Swine1

R. W. Swick, R. H. Grummer and C. A. Baumann

University of Wisconsin2

Abstract

  1. Weanling pigs were depleted of vitamin A and were then rendered either hyperthyroid with iodinated casein or hypothyroid with thiouracil, and then were given carotene for 16–21 days. Essentially similar stores of vitamin A were found in the livers and kidneys of the 3 groups, with a suggestion of increased stores in hyperthyroid animals that were free from diarrhea.
  2. When a large dose of carotene was given six to seven hours before slaughter, there was a marked increase (up to 20-fold) in the concentration of vitamin A in the mesenteric lymph and a much smaller rise in the blood plasma and intestinal wall. The results favor the view that carotene is converted into vitamin A in the intestinal wall of the pig.


Footnotes

1 Published with the approval of the Director of the Wisconsin Agricultural Experiment Station, Madison.

2 Departments of Biochemistry and Animal Husbandry, Madison, Wisconsin.







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