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Riboflavin Deficiency in Baby Pigs¹

University of Idaho^,3

Abstract

Riboflavin deficiency of baby pigs is associated with alopecia, anorexia, poor growth, rough hair coat, dermatitis, scours, ulcerative colitis, inflammation of anal mucosa, vomiting, light sensitivity, unsteady gait, and many abnormal internal complications.

The supplementation of 1 to 1.5 mgs. of riboflavin per day for 16 days cured the external symptoms. However, many of the internal tissue changes were not corrected. This may have been due to insufficient amounts of riboflavin being fed, or the supplementation was for too short a period of time.

¹ Published with the approval of the Director of the Idaho Agricultural Experiment Station as Research Paper No. 345.

² Departments of Animal Husbandry and Agricultural Chemistry.

³ We wish to acknowledge the assistance of W. V. Hartwell and R. V. Dahlstrom who helped care for animals used in the experiment. Credit is due Dr. L. H. Scrivner and Dr. W. B. Ardrey for assistance with post mortem studies.

We are also indebted to Merck and Company, Rahway, New Jersey, through the courtesy of Dr. D. F, Green, for supplies of thiamin, riboflavin, pyridoxine, nicotinic acid, inositol, choline, p-Aminobenzoic acid, biotin, calcium pantothenate and tocopherol; to Lederle Laboratories Inc., Pearl River, New York, through the courtesy of Dr. E. R. L. Stockstad, for pteroyl-glutamic acid; to E. I. du Pont de Nemours and Company, New Brunswick, New Jersey, through the courtesy of Dr. S. Waddell, for crystalline vitamin D₃.