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The Relationship of Protein to Pantothenic Acid and Vitamin B₁₂ in the Growing Pig¹

Michigan Agricultural Experiment Station

Abstract

Symptoms of pantothenic acid deficiency were produced in pigs fed a low protein (14 percent) ration containing corn, soybean oil meal, fish solubles and minerals. The addition of calcium pantothenate at a level of 4 mg. per pound of feed resulted in a very marked growth response.

The addition of calcium pantothenate to a higher protein (17.8 percent) ration, made up of the same feed constituents and containing the same level of pantothenic acid, resulted in only a slight increase in growth. However, this increase was not statistically significant.

The addition of vitamin B₁₂ to both basal rations did not result in any significant growth response.

The data seem to indicate that higher levels of protein exert a sparing effect on the pantothenic acid requirement of the pig.

¹ Published with the approval of the Director of the Michigan Agricultural Experiment Station as Journal Article No. 1314.

² Departments of Agricultural Chemistry, Animal Husbandry and Animal Pathology, Michigan State College, East Lansing. This work was supported, in part, by a grant from Merck & Co., Inc., Rahway, New Jersey.