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Pyridoxine Deficiency in Baby Pigs¹

University of Idaho, The State College of Washington^{,3, 4, 5}

Abstract

In these experiments pyridoxine deficiency in baby pigs was characterized by poor appetite, incoordination of the muscles, spastic gait, poor growth, epileptiform fits, comas, rough hair coat, brown exudate around the eyes, and impairment of eyesight.

The adequate supplementation of pyridoxine cured all the symptoms with the exception of the impairment of eyesight.

¹ Published with the approval of the Director of the Idaho Agricultural Experiment Station as Research Paper No. 317, and as Scientific Paper No. 948, Washington Agricultural Experiment Stations, Institute of Agricultural Sciences, The State College of Washington, Pullman.

² Assistant Professor of Animal Husbandry and Assistant Animal Husbandman, Agricultural Experiment Station, the University of Idaho; Professor and Head, Department of Agricultural Chemistry and Agricultural Chemist, Agricultural Experiment Station, the University of Idaho;formerly Assistant Professor of Agricultural Chemistry and Assistant Agricultural Chemist, Agricultural Experiment Station, the University of Idaho. Present address: Department of Biochemistry, University of Louisville Medical School, Louisville, Ky.; Professor and Chairman, Department of Animal Husbandry and Animal Husbandman, Agricultural Experiment Station, The State College of Washington, respectively.

³ From a thesis to be submitted by W. P. Lehrer, Jr., in partial fulfillment of the requirements for the Ph.D. degree, The State College of Washington.

⁴ Experimental work done at the University of Idaho, Moscow.

⁵ We are indebted to Dr. D. R. Green, Merck and Co., Rahway, N. J., for supplies of thiamine, riboflavin, pyridoxine, nicotinic acid, inositol, choline, p-aminobenzoic acid, biotin, calcium pantothenate and alpha-tocopherol; to Dr. E. L. R. Stockstad, Lederle Laboratories, Inc., Pearl River, N. Y., for pteroylglutamic acid; and to Dr. J. Waddell, E. I. du Pont de Nemours Co., New Brunswick, N. J., for crystalline vitamin D₃.

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