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The Effect of Thyroprotein on the Growth and Thyrotropic Hormone Content of the Anterior Pituitary of Swine^{1, 2}

Purdue University Agricultural Experiment Station

Abstract

In the trials reported in this paper the only instances in which the feeding of thyroprotein resulted in an increased growth rate in swine were those in which the level of thyroprotein fed per unit of body weight decreased as the animals grew larger. (Trial I, Lot V; Trial III, Lots II and V).

The feeding of thyroprotein to hogs on pasture in no case stimulated growth rate and in one instance (Trial II. Lot III) depressed growth rate significantly.

Animals which consumed the highest levels of thyroprotein, per unit of body weight, had anterior hypophyses with the lowest assays of thyrotropic hormone.

¹ Contribution from the Department of Animal Husbandry, Journal Paper No. 490, Purdue University Agricultural Experiment Station, Lafayette, Indiana.

² A condensation of a portion of the thesis presented to the Graduate Faculty at Purdue University by the senior author in partial fulfillment of the requirements for the degree of Doctor of Philosophy, June, 1950.

³ The authors are grateful to Kingan and Company, Indianapolis, Indiana for establishing a grant to support this research and to Dr. W. R. Graham. Tr., Cerophyl Laboratories, Kansas City, Missouri, for the thyroprotein.