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Cornell University
Abstract
For many years it has been known that raw egg white is poorly digested by such omnivorous species as dogs, rats and man. When considerable amounts of raw egg albumin are eaten by these species, severe diarrhea develops. In the white rat, the feeding of high levels of raw egg albumin not only leads to severe diarrhea, but skin lesions ultimately develop. These have been extensively studied by Boas (1927), Parsons and Lease (1934), Salmon and Goodman (1934), György (1939) and others.
Formerly these skin lesions in rats were ascribed to some toxic property of the uncooked egg white. In recent years this skin trouble has been found to be due to a deficiency in the vitamin, biotin, which was first isolated from egg yolk by the Dutch scientists, Kögl and Tönnis (1936).
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